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Invitrogen
KISS1R (extracellular) Polyclonal Antibody
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FIGURE: 1 / 3
KISS1R (extracellular) Antibody (PA5-111844) in IHC (P)
Immunohistochemistry analysis of KISS1R in paraffin-embedded rat pancreas tissue sections using KISS1R (extracellular) Antibody (Product # PA5-111844) at a dilution of 1:100. KISS1R staining (brown) appears in Isles of Langerhans (IL). Hematoxilin is used as the counterstain.
Product Details
PA5-111844
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide corresponding to amino acid residues 292-305 of human KISS1R (3rdextracellular loop)
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2857253
Product Specific Information
Reconstitute antibody with 50 µL of double distilled water (DDW). The reconstituted solution can be stored at 4 degrees C for up to 1 week. For longer periods, small aliquots should be stored at -20 degrees C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Peptide sequence is: (C)GSWHPRS YAAYALK
Homology: Rat - 13/14 amino acid residues identical; mouse - 12/14 amino acid residues identical.
Target Information
GCPR54 is a galanin-like G protein coupled receptor that binds metastin, a peptide encoded by the metastasis suppressor gene KISS1. The tissue distribution of the protein suggests that it is involved in the regulation of endocrine function, and this is supported by the finding that it appears to play a role in the onset of puberty. GPR54 has been reported in various human brain regions, placenta, pancreas, and spinal cord, and at lower levels in spleen, peripheral blood leukocytes, testis, lymph node, thymus, small intestine, stomach, lung, and kidney. The receptor is also abundant in tumor tissues. In rat, GPR54 is expressed in liver, intestine, and in the pons, midbrain, thalamus, hypothalamus, hippocampus, amygdala, cortex (including frontal), and striatum. ESTs have been isolated from normal placenta and kidney cancer libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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