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Invitrogen
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Immunogen sequence: VTLSIEPQTV QEGERVVFTC QATANPEILG YRWAKGGFLI EDAHESRYET NVDYSFFTEP VSCEVHNKVG STNVSTLVNV HFAPRIVVDP KPTTTDIGSD VTLTCVWVGN PPLTLTWTKK DSNMVLSNSN QLLLKSVTQA DA
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.
KIRREL (NEPH1) is a member of the nephrin-like protein family, which includes NEPH2 and NEPH3. The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. NEPH1 is a member of the nephrin-like protein family, which includes NEPH2. The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration (Sellin et al., 2003).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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