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Invitrogen
KIAA1456 Polyclonal Antibody
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FIGURE: 1 / 2
KIAA1456 Antibody (PA5-70320) in WB
Nature communications 2022 -
Effect of KIAA1456 overexpression and depletion on mcm 5 U and mcm 5 s 2 U modification levels and on CHIKV infection. a Western blot showing KIAA1456 protein upregulation upon CHIKV infection. Values denote relative KIAA1456 expression normalized by tubulin expression calculated from 3 independent replicates and expressed as mean +- SEM. b Western blot showing KIAA1456 protein levels under plasmid-driven o... View More
Product Details
PA5-70320
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
synthetic peptide directed towards the N-terminal region of human KIAA1456
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2689520
Product Specific Information
This target displays homology in the following species: Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Target Information
C8orf79 (chromosome 8 open reading frame 79) is a 454 amino acid protein that belongs to the methyltransferase superfamily and is encoded by a gene that maps to human chromosome 8p22. Consisting of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and are typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Probable tRNA methyltransferase 9-like protein; Probable tRNA methyltransferase 9B; RM9L
Gene Aliases: C8orf79; KIAA1456; TRM9L; TRMT9B
UniProt ID: (Human) Q9P272
Entrez Gene ID: (Human) 57604
tRNA binding
tRNA methyltransferase activity
ferrous iron binding
tRNA (uracil) methyltransferase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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