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Immunogen sequence: SRSVRQVYEV HDSDDWTIHD FECPMECFCP PSFPTALYCE NRGLKEIPAI PSRIWYLYL
Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 77%.
Keratocan (KTN), also known as keratan sulfate proteoglycan keratocan, is a protein that in humans is encoded by the KERA gene. It is mapped to 12q22. The protein encoded by this gene is a keratan sulfate proteoglycan that is involved in corneal transparency. Defects in this gene are a cause of autosomal recessive cornea plana 2 (CNA2). Keratan sulfate proteoglycans (KSPGs) are members of the small leucine-rich proteoglycan (SLRP) family. KSPGs, particularly keratocan, lumican and mimecan, are important to the transparency of the cornea.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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