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Invitrogen
KCNK18 (extracellular) Polyclonal Antibody
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FIGURE: 1 / 5
KCNK18 (extracellular) Antibody (PA5-77636) in ICC/IF
Immunocytochemistry analysis of KCNK18 (extracellular) in paraformaldehyde-fixed and permeabilized mouse/rat neuroblastoma and dorsal root ganglion neuron. A) Samples were probed with KCNK18 (extracellular) polyclonal antibody (Product # PA5-77636) at a dilution of 1:50, and incubated with goat anti-rabbit-AlexaFluor-555 and Hoechst. Visible light images are shown in Panel B.
Product Details
PA5-77636
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide (C)EAEENPELKKFLDD, corresponding to amino acid residues 62-75 of mouse K2P 18.1
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2736001
Product Specific Information
Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 µL of deionized water.
Target Information
TRESK (TWIK-related spinal cord K+ channel) is a two-pore domain K+ channel that induces outward rectification and functions as a background K+ channel that is abundantly expressed in the spinal cord, thymus, spleen, and leukemic T-lymphocytes. TRESK is activated by increased cytoplasmic calcium concentration through calcineurin as well as by acetylcholine and histamine. It has been suggested that TRESK is linked to acute and chronic pain by activation of calcineurin. Other studies indicate that TRESK may play a role in the regulation of T-cell function and could be an excellent target to treat T-cell originated immune dysfunction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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