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Invitrogen
KCC2 Polyclonal Antibody
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FIGURE: 1 / 1
KCC2 Antibody (PA5-69278) in WB
Western blot was performed using Anti-KCC2 Polyclonal Antibody (Product # PA5-69278) and ~126 kDa band corresponding to KCC2 was observed in Mouse Brain and Rat Brain, but not in Mouse Stomach and Rat Stomach as reported An uncharacterized band at ~40 kDa was observed in the Brain tissues tested. Tissue lysate (40 µg lysate) of Mouse Brain (Lane 1), Rat Brain (Lane 2), Mouse Stomach (Lane 3), and Rat Stomach (Lane 4) were electrophoresed using Novex® NuPAGE® 4-12 % Bis-Tris gel (Product # NP0322BOX). Resolved proteins were then transferred... View More
Product Details
PA5-69278
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
synthetic peptide corresponding to a region of mouse KCC2
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2691208
Product Specific Information
This target displays homology in the following species: Cow: 100%; Dog: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Target Information
Mediates electroneutral potassium-chloride cotransport in mature neurons. Transport occurs under isotonic conditions, but is activated 20-fold by cell swelling. Important for Cl(-) homeostasis in neurons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Electroneutral potassium-chloride cotransporter 2; K-Cl cotransporter 2; KCC 2; KCC2a variant 1; KCC2a-S25 variant 1; KCC2b variant 2; mKCC2; Neuronal K-Cl cotransporter; S12A5; Solute carrier family 12 member 5
Gene Aliases: KCC2; Kiaa1176; mKIAA1176; Slc12a5
UniProt ID: (Mouse) Q91V14
Entrez Gene ID: (Mouse) 57138
transport
ion transport
potassium ion transport
chloride transport
chemical synaptic transmission
learning
organic cation transport
ammonium transport
multicellular organism growth
thermosensory behavior
response to drug
intracellular pH reduction
transmembrane transport
ammonium transmembrane transport
cation transmembrane transport
chloride transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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