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Immunogen sequence: VITVDVSIFL PGSINITAPQ CHDGQQPVNC LNVTTCFSFH GKHVPEEIGL NYVLMADVAK KEKGQMPRVY FVLLGETMGQ VTEKLQLTYM EETCRHYVAH VK
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 85%.
This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an integrin that is a receptor for VCAM1, cytotactin and osteopontin. Expression of this gene has been found to be upregulated in small cell lung cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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