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Invitrogen
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Immunogen sequence: KGKLVVGHDLK HDFQALKEDM SGYTIYDTST DRLLWREAKL DHCRRVSLRV LSERLLHKSI QNSLLGHSSV EDA
Highest antigen sequence identity to the following orthologs - mouse 80%, rat 78%.
Interferon-induced antiviral exoribonuclease that acts on single-stranded RNA and also has minor activity towards single-stranded DNA. Exhibits antiviral activity against RNA viruses including hepatitis C virus (HCV), hepatitis A virus (HAV) and yellow fever virus (YFV) in an exonuclease-dependent manner. May also play additional roles in the maturation of snRNAs and rRNAs, and in ribosome biogenesis. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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