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Invitrogen
IRF1 Polyclonal Antibody
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FIGURE: 1 / 9
IRF1 Antibody (PA5-64093) in ICC/IF
Immunofluorescence analysis of IRF1 was performed using 70% confluent log phase Hep G2 cells treated with Human IFN Gamma (250IU/mL for 24hr). The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 45 minutes at room temperature. The cells were labeled with IRF1 Polyclonal Antibody (Product # PA5-64093) at 1:200 dilution in 0.1% BSA, incubated at 4 degree celsius overnight and then labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Recombinan... View More
Product Details
PA5-64093
Applications
Tested Dilution
Publications
Product Specifications
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human IRF1
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2642775
Product Specific Information
Immunogen sequence: SAVRVYRMLP PLTKNQRKER KSKSSRDAKS KAKRKSCGDS SPDTFSDGLS SSTLPDDHSS YTVPGYMQDL EVEQALTP
Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 82%.
Target Information
IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppression. Diseases associated with IRF1 include gastric cancer, somatic and lung cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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