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This target displays homology in the following species: Cow: 79%; Dog: 79%; Horse: 86%; Human: 100%; Pig: 86%; Rabbit: 79%
IGF-binding proteins prolong the half-life of IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs in cell culture. They alter the interaction of IGFs with their cell surface receptors. May be a putative tumor suppressor protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: IGFBP; IGFBP-related protein 10; IGFBP-rP4; Insulin like growth factor binding protein; insulin like growth factor binding protein-like 1; insulin-like growth factor binding protein related protein 4; insulin-like growth factor binding protein-like 1; Insulin-like growth factor-binding protein-like 1; Insulin-like growth factor-binding-related protein 4
Gene Aliases: bA113O24.1; IGFBP-RP4; IGFBPL1; IGFBPRP4
UniProt ID: (Human) Q8WX77
Entrez Gene ID: (Human) 347252
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