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Invitrogen
HSPB8 Polyclonal Antibody
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HSPB8 Antibody (PA1-31842) in WB
Western blot analysis of HSPB8/Heat Shock Protein beta 8 in human Muscle lysate (RIPA buffer, 30g total protein per lane) using a HSPB8/Heat Shock Protein beta 8 polyclonal antibody (Product # PA1-31842) at a dilution of 1g/ml following incubation for 1 hour and detected using chemiluminescence.
Product Details
PA1-31842
Product Specifications
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide with sequence NELPQDSQEVTCT, from C Terminus of the protein sequence according to NP_055180
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2233324
Product Specific Information
PA1-31842 detects HSPB8 from human samples.
PA1-31842 has been successfully used in Western blot applications.
The PA1-31842 immunogen is: Peptide with sequence NELPQDSQEVTCT, from C Terminus of the protein sequence according to NP_055180
Target Information
The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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