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PA1-24444 detects HOXD3 in Human samples.
PA1-24444 has been successfully used in Western Blot procedures.
PA1-24444 immunogen corresponds to Polyclonal antibody from rabbits immunized with a synthetic peptide region of human HOXD3.
HOXD3 (homeobox D3) belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that remove the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. HOXD3 may play a role in the regulation of cell adhesion processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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