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Invitrogen
HOXB8 Polyclonal Antibody
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FIGURE: 1 / 5
HOXB8 Antibody (PA5-81200) in WB
Western Blot using HOXB8 Polyclonal Antibody (Product # PA5-81200) at 1:500 dilution. Lane A: Mouse brain tissue lysate, Lane B: Rat brain tissue lysate. Lysates/proteins at 30 µg per lane. Secondary Goat Anti-Rabbit IgG H&L (DyLight™ 800) at 1:10,000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size: 28 kDa. Observed band size: 28 kDa. (We are unsure of the identity of these extra bands).
Product Details
PA5-81200
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to the center region of the Human HOXB8
Conjugate
Form
Liquid
Concentration
5 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2788429
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human HOXB8.
Target Information
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: homeo box 2D; homeo box B8; Homeobox protein Hox-2.4; Homeobox protein Hox-2D; Homeobox protein Hox-B8
Gene Aliases: Hox-2.4; HOX2; HOX2D; HOXB8
UniProt ID: (Human) P17481
Entrez Gene ID: (Human) 3218
transcription, DNA-templated
regulation of transcription, DNA-templated
grooming behavior
adult locomotory behavior
anterior/posterior pattern specification
sensory perception of pain
dorsal spinal cord development
negative regulation of myeloid cell differentiation
embryonic skeletal system morphogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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