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Invitrogen
HOXB7 Polyclonal Antibody
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HOXB7 Antibody (PA5-48725) in IHC (P)
Immunohistochemical analysis of Mouse Hoxb7 in formalin fixed and paraffin embedded mouse jejunum tissue. Samples stained using a Mouse Hoxb7 Antibody (Center) (Product # PA5-48725), followed by peroxidase conjugation of the secondary antibody and DAB staining.
Product Details
PA5-48725
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 94-122 amino acids from the Central region of mouse Hoxb7.
Conjugate
Form
Liquid
Concentration
Lot-Specific
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2634182
Product Specific Information
Predicted to react with bovine and rat based on sequence homology.
Target Information
The homeobox genes encode transcription factors that regulate developmental processes such as body patterning and organogenesis. The mammalian HOX gene complex consists of 39 genes that are located on 4 linkage groups (clusters), dispersed over 4 chromosomes (HOXA, HOXB, HOXC and HOXD). HOXB7 is expressed in most malignant T-cell lines and CD4-positive peripheral blood cells, and is constitutively expressed in both melanoma primary lesions and cell lines. HOXB7 binds to and transactivates bFGF in melanoma cell lines but SkBr3 breast adenocarcinoma is negative for the expression of both HOXB7 and bFGF genes. HOXB7 may be a key activator of tumor-associated neoangiogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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