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Invitrogen
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Immunogen sequence: ASKTPVGFIG LGNMGNPMAK NLMKHGYPLI IYDVFPDACK EFQDAGEQVV SSPADVAEKA DRIITMLPTS INAIEAYSGA NGILKKVKKG SLLIDSSTID PAVSKELAKE VEKMGAVFMD APVSGGVGAA RSGNLTFMVG GVEDEFAAAQ ELLGCMGSNV VYCGAVGTGQ AAKICNNMLL AISMIGTAEA MNLGIRLGLD PKLLAKILNM SSGRCWSSDT YNPVPGVMDG VPSANNYQGG FGTTLMAKDL GLAQDSATST KSPILLGSLA HQIYRMMCAK GYSKKDFSSV FQFLREEETF; Positive Samples: A-431, A-549, HepG2, 293T, Mouse heart, Mouse liver, Mouse brain, Rat heart; Cellular Location: Mitochondrion
3-hydroxyisobutyrate dehydrogenase (3-hydroxy-2-methylpropanoate:NAD(+) oxidoreductase, EC 1.1. 1.31) is a dimeric mitochondrial enzyme that catalyzes the NAD(+)-dependent, reversible oxidation of 3-hydroxyisobutyrate, an intermediate of valine catabolism, to methylmalonate semialdehyde.
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