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Invitrogen
HDAC2 Polyclonal Antibody
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Product Details
PA1-26832
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide, conjugated to KLH, corresponding to residues C-S(471) G E K T D T K G T K S E Q L S N P(488) of human HDAC 2.
Conjugate
Form
Liquid
Concentration
15 mg/mL
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
Product Specific Information
PA1-26832 detects HDAC2 from human, mouse, and rat samples. PA1-26832 is expected to cross react with chicken (94% conserved) due to sequence homology.
PA1-26832 has been successfully used in immunoprecipitation, ChIP assay and Western blot procedures. Perform enzymatic antigen retrieval before commencing with IHC staining protocol. The predicted molecular weight of PA1-26832 is 55.3 kDa.
The PA1-26832 immunogen is a synthetic peptide, conjugated to KLH, corresponding to residues C-S(471) G E K T D T K G T K S E Q L S N P(488) of human HDAC 2.
Target Information
HDAC2 belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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