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PA1-20319 detects HAND1 in mouse and rat samples. Antibody is expected to cross-react with human (100%) and rabbit (92%) based on sequence homology.
PA1-20319 has been successfully used in immunohistochemistry and Western blot procedures.
Positive control: Embryonic mouse brain.
The PA1-20319 immunogen is a synthetic peptide, BSA conjugated, correspondiong to the residues K(168) A D G G R E S K R K R E L(181) of to human HAND1.
Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.
HAND1 belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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