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PA1-25828 detects Ghrelin from mouse, and rat samples. PA1-25828 is expected to cross react with feline (92% conserved), gerbil (92% conserved), Macaque monkey (92% conserved), and porcine (92% conserved) due to sequence homology.
PA1-25828 has been successfully used in Western blot procedures.
The PA1-25828 immunogen is a synthetic peptide corresponding to the N14 region residues G(24) S S (n Octanoyl) F L S P E H Q K A Q Q(37) of Ghrelin.
GHRL encodes ghrelin-obestatin preproprotein, which generates ghrelin and obestatin. Ghrelin is an the ligand for the growth hormone secretagogue receptor type 1 and is involved in regulating growth hormone release. Ghrelin has an appeptite-stimulating effect and induces adiposity and stimulates gastric acid secretion. Obestatin may be the ligand for the orphan G protein-coupled receptor GPR39 and is involved in satiety and can have an appetite-reducing effect resulting in decreased food intake.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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