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Invitrogen
GTF2E1 Polyclonal Antibody
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GTF2E1 Antibody (PA5-48693) in IHC (P)
Immunohistochemical analysis of GTF2E1 in formalin fixed and paraffin embedded human stomach tissue. Samples were probed with a GTF2E1 Antibody (N-term) (Product # PA5-48693) followed by peroxidase conjugation of the secondary antibody and DAB staining.
Product Details
PA5-48693
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 93-121 amino acids from the N-terminal region of human GTF2E1.
Conjugate
Form
Liquid
Concentration
Lot-Specific
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2634150
Product Specific Information
Predicted to react with bovine based on sequence homology.
Target Information
The general transcription factor TFIIE has an essential role in eukaryotic transcription initiation together with RNA polymerase II and other general factors. Human TFIIE consists of two subunits of relative molecular mass 57, 000 (TFIIE-alpha) and 34, 000 (TFIIE-beta) and joins the preinitiation complex after RNA polymerase II and TFIIF. TFIIE-alpha is necessary for transcription initiation together with TFIIE-beta, and recombinant TFIIE-alpha can fully replace the natural subunit in an in vitro transcription assay. Its sequence contains several interesting structural motifs (leucine repeat, zinc finger and helix-turn-helix) and sequence similarities to bacterial sigma factors that suggest direct involvement in the regulation of transcription initiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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