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Invitrogen
GPD2 Polyclonal Antibody
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GPD2 Antibody (PA5-48386) in IHC (P)
Immunohistochemical analysis of GPD2 in formalin fixed and paraffin embedded human pancreas tissue. Samples were probed with a GPD2 Antibody (C-term) (Product # PA5-48386) followed by peroxidase conjugation of the secondary antibody and DAB staining.
Product Details
PA5-48386
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 606-634 amino acids from the C-terminal region of human GPD2.
Conjugate
Form
Liquid
Concentration
Lot-Specific
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2633843
Product Specific Information
Predicted to react with bovine, monkey and mouse based on sequence homology.
Target Information
Mitochondrial glycerophosphate dehydrogenase (EC 1. 1. 99. 5), or GPD2, is located on the outer surface of the inner mitochondrial membrane and catalyzes the unidirectional conversion of glycerol-3-phosphate (G-3-P) to dihydroxyacetone phosphate (DHAP) with concomitant reduction of the enzyme-bound FAD. Together with a cytosolic NAD-linked GPD (GPD1; MIM 138420), GPD2 forms the glycerol phosphate shuttle, which uses the interconversion of G-3-P and DHAP to transfer reducing equivalents into mitochondria, resulting in the reoxidation of NADH formed during glycolysis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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