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PA1-31024 detects GGA1 from human samples.
PA1-31024 has been successfully used in immunofluorescence, Western blot applications.
The PA1-31024 immunogen is: Synthetic peptide: AMPTRPGEQASPEQPSA, corresponding to amino acids 336-352 of Human GGA1.
This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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