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Immunogen sequence: DPRSLCRCAQ VCWHWKNLAE LDQLWMLKCL RFNWYINFSP TPFEQGIWKK HYIQMVKELH ITKPKTPPKD GFVIADVQL
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 87%.
This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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