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Invitrogen
Factor VII Polyclonal Antibody, FITC
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Product Details
PA1-74109
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Sheep
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Factor VII from human plasma.
Conjugate
Excitation/Emission Max
498/517 nm
View spectra
Form
Liquid
Concentration
1 mg/mL
Storage conditions
4°C, store in dark
Shipping conditions
Wet ice
RRID
AB_1090083
Product Specific Information
PA1-74109 detects Factor VII from human samples.
PA1-74109 has been successfully used in ELISA and FACS applications.
The PA1-74109 immunogen is Factor VII from human plasma.
Target Information
Coagulation factor VII is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in F7 production can cause coagulopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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