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Invitrogen
FRS2 Polyclonal Antibody
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FRS2 Antibody (PA5-27875) in IHC (P)
FRS2 Polyclonal Antibody detects FRS2 protein at membrane on HSC-3 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded HSC-3 xenograft. FRS2 Polyclonal Antibody (Product # PA5-27875) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
Product Details
PA5-27875
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 1 and 232 of Human FRS2
Conjugate
Form
Liquid
Concentration
1 mg/mL
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2545351
Product Specific Information
Recommended positive controls: PC-3.
Predicted reactivity: Mouse (97%), Rat (96%), Xenopus laevis (87%), Pig (99%), Chicken (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1. [UniProt]
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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