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FIGURE: 1 / 1
Immunogen sequence: LEEDLQDDEI EMLVDDPRDL EQMNEESLEV SPDMCIYITE DMLMSRKLNG HSGLIVKEIG SSTSSSSETV VKLRGQSTDS LPQTICRKPK TSTDRHSLSL DDIRLYQKDF LRIAGLCQDT AQSYTFGCGH ELDEE
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%.
The protein encoded by this gene interacts with signaling pathways to coordinately regulate cell growth, cell proliferation, apoptosis, autophagy, and cell migration. This tumor suppressor also enhances retinoblastoma 1 gene expression in cancer cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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