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Invitrogen
FPR2 Polyclonal Antibody
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FPR2 Antibody (PA5-33538) in IHC (P)
Immunohistochemical analysis of formalin-fixed paraffin-embedded human colon, uc, neutrophils in crypt abscess using a FPR2/FPRL1 polyclonal antibody (Product # PA5-33538) at a 8 ug/ml dilution. Heat-induced antigen retrieval was performed prior to staining.
Product Details
PA5-33538
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 16 amino acid peptide from C-terminus of human FPR2 / FPRL1.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla (100%) Chimpanzee, Monkey (94%) Orangutan, Marmoset (88%) Rabbit (81%).
Target Information
Formyl peptide receptor 2 (FPR2) is a low affinity receptor for N-formyl-methionyl peptides. Binding of FMLP to FPR2 causes activation of neutrophils. The response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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