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Invitrogen
FNBP4 Polyclonal Antibody
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FIGURE: 1 / 3
FNBP4 Antibody (PA5-103846) in ICC/IF
Immunocytochemistry analysis of FNBP4 in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with FNBP4 polyclonal antibody (Product # PA5-103846) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Product Details
PA5-103846
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human FNBP4(Accession Q8N3X1), corresponding to amino acid residues Q983-T1017.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2853178
Product Specific Information
Antibody detects endogenous levels of total FNBP4.
Target Information
FNBP4 encodes a protein containing two tryptophan-rich WW domains that binds the proline-rich formin homology 1 domains of formin family proteins, suggesting a role in the regulation of cytoskeletal dynamics during cell division and migration. It also binds intersectin family proteins suggesting a role in the maintenance of membrane curvature at sites of nascent vesicle formation. Naturally occurring mutations in this gene are associated with Waardenburg anophthalmia syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: formin binding protein 30; Formin-binding protein 30; Formin-binding protein 4
Gene Aliases: FBP30; Fnbp30; FNBP4; KIAA1014; mKIAA1014
UniProt ID: (Human) Q8N3X1, (Mouse) Q6ZQ03
Entrez Gene ID: (Human) 23360, (Mouse) 55935
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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