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This gene encodes a filamin A binding protein. The encoded protein promotes the degradation of filamin A and may regulate cortical neuron migration and dendritic spine morphology. Mice lacking a functional copy of this gene exhibit reduced dendritic spine length and altered excitatory signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Filamin-A-interacting protein 1; FILIP
Gene Aliases: FILIP; FILIP1; KIAA1275
UniProt ID: (Human) Q7Z7B0
Entrez Gene ID: (Human) 27145
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