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Immunogen sequence: QEVLNLTKEL ELSKRYSRAL RPSVNGRRMV DVPVTSTGVQ TDAVSGEAAE EETPAVFIRK SFQEENHIMS NLRQVGLKKP VE
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 91%.
This gene encodes a filamin A binding protein. The encoded protein promotes the degradation of filamin A and may regulate cortical neuron migration and dendritic spine morphology. Mice lacking a functional copy of this gene exhibit reduced dendritic spine length and altered excitatory signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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