Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Abnova
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Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MLKKISVGVA GDLNTVTMKL GCVLMAWALY LSLGVLWVAQ MLLAASFETL QCEGPVCTEE SSCHTEDDLT DAREAGFQVK AYTFSEPFHL IVSYDWLILQ GPAKPVFEGD LLVLRCQAWQ DWPLTQVTFY RDGSALGPPG PNREFSITVV QKADSGHYHC SGIFQSPGPG IPETASVVAI TVQELFPAPI LRAVPSAEPQ AGSPMTLSCQ TKLPLQRSAA RLLFSFYKDG RIVQSRGLSS EFQIPTASED HSGSYWCEAA TEDNQVWKQS PQLEIRVQGA SSSAAPPTLN PAPQKSAAPG TAPEEAPGPL PPPPTPSSED PGFSSPLGMP DPHLYHQMGL LLKHMQDVRV LLGHLLMELR ELSGHRKPGT TKATAE
Receptors for the Fc fragment of IgG, or FCGRs (see MIM 146790), are cell surface glycoproteins of the Ig superfamily (IgSF). These receptors mediate phagocytosis of IgG-coated pathogens and promote activation of effector cells, leading to inflammatory responses and antibody-mediated cellular cytotoxicity. All FCGR genes map to human chromosome 1. Additional genes in this region, including FREB, encode FCGR homologs that are selectively expressed in B cells and may be implicated in B-cell development and lymphomagenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Fc receptor homolog expressed in B cells (FREB); Fc receptor homolog expressed in B-cells; Fc receptor related protein X; Fc receptor-like A; Fc receptor-like and mucin-like 1; Fc receptor-like and mucin-like protein 1; Fc receptor-like protein; Fc receptor-related protein X; FcRX
Gene Aliases: FCRL; FCRL1; FCRLA; FCRLb; FCRLc1; FCRLc2; FCRLd; FCRLe; FCRLM1; FCRLX; FCRX; FREB; UNQ291/PRO329
UniProt ID: (Human) Q7L513
Entrez Gene ID: (Human) 84824
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