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Proteintech
FC tag Polyclonal Antibody
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Product Details
28108-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein
Conjugate
Form
Liquid
Purification
Antigen affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: PRGPTIKPCP PCKCPAPNLL GGPSVFIFPP KIKDVLMISL SPIVTCVVVD VSEDDPDVQI SWFVNNVEVH TAQTQTHRED YNSTLRVVSA LPIQHQDWMS GKEFKCKVNN KDLPAPIERT ISKPKGSVRA PQVYVLPPPE EEMTKKQVTL TCMVTDFMPE DIYVEWTNNG KTELNYKNTE PVLDSDGSYF MYSKLRVEKK NWVERNSYSC SVVHEGLHNH HTTKSFSRTP GK
Target Information
The FC antibody fragment refers to a specific part of an antibody molecule, known as the fragment crystallizable region. It plays a crucial role in the immune response and has important functions in antibody-mediated immune reactions. The structure of the FC antibody fragment typically consists of the constant region of the antibody heavy chain. This region contains a specific amino acid sequence that allows the fragment to bind to various immune cells and molecules, such as Fc receptors and complement proteins. The FC fragment is responsible for initiating effector functions, such as antibody-dependent cellular cytotoxicity (ADCC), antibody-dependent cellular phagocytosis (ADCP), and complement-dependent cytotoxicity (CDC). The FC antibody fragment acts as a bridge between the antibody and the immune system, facilitating the elimination of pathogens, infected cells, or other foreign substances. In addition to its immune functions, the FC region also plays a role in antibody stability and half-life. It can influence the pharmacokinetics and biodistribution of therapeutic antibodies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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