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Invitrogen
FBXO45 Polyclonal Antibody
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Product Details
PA5-59271
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human FBXO45
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2641553
Product Specific Information
Immunogen sequence: VIGIATKRAP MQCQGYVALL GSDDQSWGWN LVDNNLLHNG EVNGSFPQCN NAPKYQIGER IRVILDMEDK TLAFERGYEF LGVAFRGLPK VCL
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
Target Information
Component of E3 ubiquitin ligase complexes. Required for normal neuromuscular synaptogenesis, axon pathfinding and neuronal migration. Plays a role in the regulation of neurotransmission at mature neurons. May controls synaptic activity by controlling UNC13A via ubiquitin dependent pathway. Specifically recognizes TP73, promoting its ubiquitination and degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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