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Additional Information: This antibody is expected to recognize isoform 1 and 2 (NP_036308.1; NP_277019.1).
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:8,000.
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: F-box only protein 4; F-box protein Fbx4
Gene Aliases: FBX4; FBXO4
UniProt ID: (Human) Q9UKT5
Entrez Gene ID: (Human) 26272
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