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Abnova
FBXO33 Polyclonal Antibody, MaxPab™
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Product Details
H00254170-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FBXO33 (NP_976046.1, 1 a.a. approximately 555 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5-1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MLLFLSVPQP RPPGARTRAG AARVARWRRL RLQQLRRLRG LLRVLRGRPG AGSRRRGRMA LCGQAAGAAS LPSELIVHIF SFLPAPDRLR ASASCSHWRE CLFYPALWPQ LRICLRVSPA EQPRLEFLMR KCGWFVRELR VEFAAENYLS GGGPGDGGGA DTGTGGEEVE ALQLSARWLE VLRTYLELVL CVLVSIRNNR NLQKFSLFGD ISVLQQQGSL SNTYLSKVDP DGKKIKQIQQ LFEEILSNSR QLKWLSCGFM LEIVTPTSLS SLSNAVANTM EHLSLLDNNI PGNSTLITAV ELERFVNLHS LALDFCDFTA EMARVLTDSN HVPLQRLSLL VHNVSVMHKS LDNMPNDEHW KALSRKSTSF RVYIMAFDIK SEDMLKILKP SIPLERIHFD SYITCVSGAI VDLISRQYDK FLTHFILMND VIDTSGFPDL SDNRNEDPLV LLAWRCTKLS LLAIHGYTVW AHNLIAIARL RGSDLKVLEV TEESIDFDQG ELADQDVDPV HNLIEQVSLG LGQPWHAVMD IESLSVFTEP NRHFYREMQS FSEDI
Target Information
FBXO33 is the substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. FBXO33 probably recognizes and binds to phosphorylated target proteins. Recognizes YBX1.Members of the F-box protein family, such as FBXO33, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin, and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: F-box only protein 33
Gene Aliases: BMND12; c14_5247; FBX33; FBXO33
UniProt ID: (Human) Q7Z6M2
Entrez Gene ID: (Human) 254170
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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