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Invitrogen
FAM213A Polyclonal Antibody
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FAM213A Antibody (PA5-48580) in IHC (P)
Immunohistochemical analysis of C10orf58 in formalin fixed and paraffin embedded human skin tissue. Samples were probed with a C10orf58 Antibody (C-term) (Product # PA5-48580) followed by peroxidase conjugation of the secondary antibody and DAB staining.
Product Details
PA5-48580
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 181-209 amino acids from the C-terminal region of human C10orf58.
Conjugate
Form
Liquid
Concentration
Lot-Specific
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2634037
Product Specific Information
Predicted to react with bovine based on sequence homology.
Target Information
Involved in redox regulation of the cell (PubMed:26438880, PubMed:19951071). Acts as an antioxidant (PubMed:19951071, PubMed:26438880). Inhibits TNFSF11-induced NFKB1 and JUN activation and osteoclast differentiation (PubMed:19951071). May affect bone resorption and help to maintain bone mass (PubMed:19951071). Acts as a negative regulator of macrophage-mediated inflammation by inhibiting macrophage production of inflammatory cytokines, probably through suppression of the MAPK signaling pathway (PubMed:26438880). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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