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Search Thermo Fisher Scientific
Invitrogen
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Immunogen sequence: WDSGFSEVSG STWREEELPV SQRPAPSAQP LRRQCLSVSG LPMPSRAPVA SVPPVHHPRP KSTPDACLEH WQGLEAEDWT AALLNRGRS
Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 76%.
FAM212A, initially identified as INCA (induced in neural crest by AP-2alpha) in xenopus, is expressed primarily in neural crest cells and their derivatives. FAM212A can associate with the P21-kinase protein PAK4 and this association modulates cytoskeletal dynamics. In mammals, FAM212A is thought to play a role in neural tube closure; a significant fraction of FAM212A-null mice exhibited exencephaly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: family with sequence similarity 212, member A; INCA; Induced in neural crest by AP2-alpha protein homolog; Inka-box actin regulator 1; PAK4-inhibitor INKA1
Gene Aliases: C3orf54; FAM212A; INKA1
UniProt ID: (Human) Q96EL1
Entrez Gene ID: (Human) 389119
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