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Invitrogen
ERCC6L Polyclonal Antibody
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Product Details
PA5-62199
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ERCC6L
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2641090
Product Specific Information
Immunogen sequence: IIWIRLVPLQ EEIYRKFVSL DHIKELLMET RSPLAELGVL KKLCDHPRLL SARACCLLNL GTFSAQDGNE GEDSPDVDHI DQVTDDTLME ESGKMIFLMD LL
Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 81%.
Target Information
ERCC6L is a DNA helicase that acts as an essential component of the spindle assembly checkpoint. ERCC6L contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. ERCC6L acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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