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Invitrogen
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This target displays homology in the following species: Cow: 93%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%
Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Epidermal growth factor receptor pathway substrate 15-related sequence; Epidermal growth factor receptor substrate 15-like 1; Eps15-related protein; Eps15-rs; Eps15R
Gene Aliases: 9830147J04Rik; AI593686; Eps15-rs; Eps15l1; Eps15R
UniProt ID: (Mouse) Q60902
Entrez Gene ID: (Mouse) 13859
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