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Invitrogen
EPS15R Polyclonal Antibody
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FIGURE: 1 / 1
EPS15R Antibody (PA5-109690) in WB
Western blot analysis of EPS15R in extracts of various cell lines. Samples were incubated with EPS15R Polyclonal antibody (Product # PA5-109690) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3s.
Product Details
PA5-109690
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 475-754 of human EPS15L1 (NP_001245304.1).
Conjugate
Form
Liquid
Concentration
3.02 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2855101
Product Specific Information
Immunogen sequence: QMISSLKTQI QSQESDLKSQ EDDLNRAKSE LNRLQQEETQ LEQSIQAGRV QLETIIKSLK STQDEINQAR SKLSQLHESR QEAHRSLEQY DQVLDGAHGA SLTDLANLSE GVSLAERGSF GAMDDPFKNK ALLFSNNTQE LHPDPFQTED PFKSDPFKGA DPFKGDPFQN DPFAEQQTTS TDPFGGDPFK ESDPFRGSAT DDFFKKQTKN DPFTSDPFTK NPSLPSKLDP FESSDPFSSS SVSSKGSDPF GTLDPFGSGS FNSAEGFADF SQMSKVKVHL
Target Information
Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epidermal growth factor receptor pathway substrate 15-like 1; Epidermal growth factor receptor substrate 15-like 1; epidermal growth factor receptor substrate EPS15R; Eps15-related protein; Eps15R
Gene Aliases: EPS15L1; EPS15R
UniProt ID: (Human) Q9UBC2
Entrez Gene ID: (Human) 58513
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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