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PA1-29134 detects DP1 from rat, human, mouse samples.
PA1-29134 has been successfully used in immunoprecipitation, Western blot applications.
The PA1-29134 immunogen is: Synthetic peptide corresponding to the N-terminus of human DP-1 protein
DP family contains at least two members, DP1 and 2. Structurally, DP1 and 2 are relatively conserved, yet their expression appears to be tissue specific. E2F 1, a functional target for the tumor suppressor protein Rb, heterodimerizes with DP1 and forms an active E2F transcriptional complex. The interaction between members of the E2F and the DP families is mediated, in part, by a leucine repeat which is weakly conserved between the two families.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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