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Immunogen sequence: VEEMLCNSFR MSAQMNRIAT HLEIKNYQND MDNMLGLAEV RQEIMNRVVN VINKVLDFRN TLETHTYLWV DDRAEFMKHF LLYGHAVS
Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 73%.
This gene encodes a ciliary outer dynein arm protein and is a member of the dynein heavy chain family. It is a microtubule-dependent motor ATPase and has been reported to be involved in the movement of respiratory cilia. Mutations in this gene have been implicated in causing Kartagener Syndrome (a combination of situs inversus totalis and Primary Ciliary Dyskinesia (PCD), also called Immotile Cilia Syndrome 1 (ICS1)) and male sterility. [provided by RefSeq, Mar 2013].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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