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PA1-4369 detects PARK7 from human and mouse samples.
PA1-4369 has been successfully used in Western blot and immunohistochemistry procedures.
The PA1-4369 immunizing peptide corresponds to amino acid residues 167-189 from human PARK7.
The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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