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Invitrogen
Cullin 3 Polyclonal Antibody
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Product Details
PA1-29163
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to the N-terminus of human Cullin-3 protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Storage conditions
4°C, do not freeze
Shipping conditions
Wet ice
RRID
AB_1957040
Product Specific Information
PA1-29163 detects Cullin 3 from mouse, human samples.
PA1-29163 has been successfully used in ICC, IF and IP applications.
The PA1-29163 immunogen is: Synthetic peptide corresponding to the N-terminus of human Cullin-3 protein.
Target Information
Cullin 3 is a member of the family of human cullin genes (CUL 1, 2, 3, 4a, 4b, and 5) homologous to the S. cerevisiae cdc 53 gene. CUL 1 forms a complex with human p19 skp1 and F box protein p45 skp2. Together with cdc 53 (Known as Cul A), as three subunits, they form a ubiquitin ligase-controlling proteolysis of G1 cell cycle regulatory proteins. In contrast to CUL 1, CUL 2 does not associate with p19 skp1 and p45 skp2. Instead, CUL 2 forms a complex with an inactive transcriptional elongation complex, SIII, formed by three subunits: Elongain C, Elongin B and VHL. The function of this association remains unknown.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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