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Invitrogen
Connexin 50 Polyclonal Antibody
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Product Details
PA5-120672
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 234-433 of human GJA8 (NP_005258.2).
Conjugate
Form
Liquid
Concentration
0.63 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2914244
Product Specific Information
Positive test controls include: Raji.
Immunogen sequence: SALKRPVEQP LGEIPEKSLH SIAVSSIQKA KGYQLLEEEK IVSHYFPLTE VGMVETSPLP AKPFNQFEEK ISTGPLGDLS RGYQETLPSY AQVGAQEVEG EGPPAEEGAE PEVGEKKEEA ERLTTEEQEK VAVPEGEKVE TPGVDKEGEK EEPQSEKVSK QGLPAEKTPS LCPELTTDDA RPLSRLSKAS SRARSDDLTV
Target Information
This gene encodes a transmembrane connexin protein that is necessary for lens growth and maturation of lens fiber cells. The encoded protein is a component of gap junction channels and functions in a calcium and pH-dependent manner. Mutations in this gene have been associated with zonular pulverulent cataracts, nuclear progressive cataracts, and cataract-microcornea syndrome.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha 8 connexin; cell surface glycoprotein; connexin 50; Connexin-50; Cx50; gap junction alpha 8; Gap junction alpha-8 protein; gap junction membrane channel protein alpha 8; gap junction membrane channel protein alpha-8; gap junction protein alpha 8 50kDa; Lens fiber protein MP70; lens intrinsic membrane protein MP70; lens opacity 10
Gene Aliases: Aey5; CAE; CAE1; Cnx50; CTRCT1; CX50; CZP1; GJA8; Lop10; MP70
UniProt ID: (Human) P48165, (Mouse) P28236
Entrez Gene ID: (Human) 2703, (Rat) 29601, (Mouse) 14616
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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