Invitrogen

Claudin 1 Polyclonal Antibody

Claudin 1 Antibody in Immunocytochemistry (ICC/IF)

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Claudin 1 Antibody (PA5-16833) in ICC/IF

Immunofluorescence analysis of Claudin 1 was performed using 90% confluent log phase Caco-2 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with Claudin 1 Rabbit Polyclonal Antibody (Product # PA5-16833) at 2 µg/mL in 0.1% BSA and incubated for 3 hours at ... View More

Claudin 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Product Details

PA5-16833

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

Immunohistochemistry (IHC)

View 4 publications 4 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200

View 1 publication 1 publication

Immunohistochemistry (Frozen) (IHC (F))

1:200

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

5 µg/ml

View 1 publication 1 publication

Product Specifications

Published species

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide derived from the C-terminus of human Claudin-1

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Wet ice

AB_10985048

Product Specific Information

PA5-16833 targets Claudin 1 in IHC (P) application and shows reactivity with Human, mouse, and Rat samples.

The PA5-16833 immunogen is a synthetic peptide derived from the C-terminus of human Claudin-1.

Target Information

Claudin-1 is a member of the transmembrane protein family claudins located in cell-cell tight junctions and it acts as a co-receptor for HCV entry into hepatic cells. Claudins are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Claudin-1 is expressed in most tissues such as bladder, fallopian tube, liver, pancreas, prostate, and skin.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Renin lineage cells repopulate the glomerular mesangium after injury.

Journal of the American Society of Nephrology : JASN

Starke C,Betz H,Hickmann L,Lachmann P,Neubauer B,Kopp JB,Sequeira-Lopez ML,Gomez RA,Hohenstein B,Todorov VT,Hugo CP

PA5-16833 was used in immunohistochemistry - frozen section to assess repopulation of glomerular mesangium after injury by renin lineage cells

Thu Jan 01 00:00:00 UTC 2015

Noninvasive delivery of siRNA and plasmid DNA into skin by fractional ablation: erbium:YAG laser versus CO₂ laser.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Lee WR,Shen SC,Chen WY,Aljuffali IA,Suen SY,Fang JY

PA5-16833 was used in immunohistochemistry to compare the relative efficacies of erbium-YAG lasers and CO2 lasers for the delivery of siRNA and plasmid DNA via fractional laser-mediated skin ablation

Tue Apr 01 00:00:00 UTC 2014

Notch signaling in the pigmented epithelium of the anterior eye segment promotes ciliary body development at the expense of iris formation.

Pigment cell & melanoma research

Sarode B,Nowell CS,Ihm J,Kostic C,Arsenijevic Y,Moulin AP,Schorderet DF,Beermann F,Radtke F

PA5-16833 was used in immunohistochemistry - paraffin section to determine the role of Notch signaling in the development of the anterior pigmented epithelium

Tue Jul 01 00:00:00 UTC 2014

Indigo naturalis upregulates claudin-1 expression in human keratinocytes and psoriatic lesions.

Journal of ethnopharmacology

Lin YK,Chen HW,Leu YL,Yang YL,Fang Y,Su Pang JH,Hwang TL

PA5-16833 was used in immunocytochemistry, immunohistochemistry, and western blot to study the elevation of claudin-1 expression in human keratinocytes and psoriatic lesions following treatment with extracts of indigo naturalis

Wed Jan 30 00:00:00 UTC 2013

Risk assessment of excess drug and sunscreen absorption via skin with ablative fractional laser resurfacing : optimization of the applied dose for postoperative care.

Lasers in medical science

Chen WY,Fang CL,Al-Suwayeh SA,Yang HH,Li YC,Fang JY

PA5-16833 was used in immunohistochemistry to study the absorption of drugs and sunscreen through the skin following ablative fractional laser resurfacing

Sun Sep 01 00:00:00 UTC 2013

An insight into the role of barrier related skin proteins.

International journal of pharmaceutics

Wato K,Hara T,Yamana K,Nakao H,Inagi T,Terada K

PA5-16833 was used in immunohistochemistry to study the effect of penetration enhancers on barrier-related proteins in skin

Thu May 10 00:00:00 UTC 2012

Claudin-1 expression in squamous cell carcinomas of different organs: comparative study of cancerous tissues and normal controls.

International journal of surgical pathology

Ouban A,Hamdan H,Hakam A,Ahmed AA

PA5-16833 was used in immunohistochemistry to study claudin-1 expression in squamous cell carcinomas of different organs

Sun Apr 01 00:00:00 UTC 2012

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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Claudin 1 Polyclonal Antibody

Claudin 1 Antibody (PA5-16833) in ICC/IF

Product Details

PA5-16833

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunohistochemistry (Frozen) (IHC (F))

Immunocytochemistry (ICC/IF)

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Performance Guarantee

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