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Rockland
Cas5 Polyclonal Antibody
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FIGURE: 1 / 1
Cas5 Antibody (600-401-948) in WB
Western blot using Rocklands affinity purified anti-hCas5 antibody shows detection of a band ~125 kDa in size corresponding to hCas5 (arrowhead). Lane 1 contains a lysate from AS cells transfected with empty vector. Lane 2 contains lysate from AS cells transfected with hCas5 (predicted MW 125 kDa). Lane 3 contains lysate from BE2 cells that have been shown to contain a high level of hCas mRNA (as tested by Northern blot). Lane 4 contains lysate from human muscle tissue that also shows high levels of hCas mRNA. Specific band reactivity is ... View More
Product Details
600-401-948
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Chimpanzee,
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to region near the amino terminal end of human Cas5 protein.
Conjugate
Form
Liquid
Concentration
1.3 mg/mL
Purification
Affinity chromatography
Storage buffer
0.02M potassium phosphate, pH 7.2, with 0.15M NaCl
Contains
0.01% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
This affinity-purified antibody is directed against human Cas5 protein. A BLAST analysis was used to suggest cross reactivity with Cas5 from human, mouse, chimpanzee, bovine, and rat based on 100% homology with the immunizing sequence. Expect cross reactivity with multiple isoforms of this protein. Cross reactivity with Cas5 from other sources has not been determined.
Target Information
The protein encoded by this gene is a zinc finger transcription factor. The encoded protein may function as a tumor suppressor, and single nucleotide polymorphisms in this gene are associated with blood pressure variation. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: castor homolog 1, zinc finger; castor zinc finger 1; Castor-related protein; Putative survival-related protein; survival-related; Zinc finger protein 693; Zinc finger protein castor homolog 1
Gene Aliases: 2410019P08Rik; AV096627; BC040081; CAS11; CASZ1; CST; D4Ertd432e; dJ734G22.1; Kiaa3026; RGD1563533; SRG; ZNF693
UniProt ID: (Human) Q86V15, (Mouse) Q9CWL2
Entrez Gene ID: (Human) 54897, (Rat) 313713, (Mouse) 69743
transcription, DNA-templated
regulation of transcription, DNA-templated
central nervous system development
regulation of neuron differentiation
multicellular organism development
negative regulation of neuron differentiation
retinal bipolar neuron differentiation
retinal rod cell fate commitment
negative regulation of retinal cone cell fate commitment
negative regulation of amacrine cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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