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Invitrogen
CNR2 Polyclonal Antibody
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CNR2 Antibody (PA5-18428) in WB
Western blot was performed using Anti-CNR2 Polyclonal Antibody (Product # PA5-18428) and a 40kDa band corresponding to CNR2 was observed across tissues tested except in Mouse Brain which is reported to be low expressing tissue for CNR2. Tissue extracts (30 µg lysate) of Mouse Spleen (Lane 1), Mouse Thymus (Lane 2), Mouse Brain (Lane 3), Mouse Ovary (Lane 4) were electrophoresed using NuPAGE™ 12% Bis-Tris Protein Gel (Product # NP0341BOX). Resolved proteins were then transferred onto a Nitrocellulose membrane (Product # IB23001) by iBlot® 2... View More
Product Details
PA5-18428
Applications
Tested Dilution
Publications
Product Specifications
Published species
Hamster,
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide sequence (TETEADGKITPWPD) corresponding to the C-terminus amino acids of CNR2 (aa 338-352).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_10984912
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
Target Information
Cannabinoids exert their well known physiological effects through two G protein coupled receptors, cannabinoid receptor 1 (CB1) and CB2. Both cannabinoid receptors have been shown to inhibit adenylyl cyclase as well as stimulate the mitogen-activated protein kinase, MAPK. CB1 receptors also modulate ion channels through direct G-protein interactions. Delta 9-tetrahydrocannibinol and related ligands likely exert their psychoactive effects by inhibiting presynaptic N- and P/Q type calcium channels. CB2 is thought to function primarily in the immune system although it has been suggested to be present in the central nervous system, including the retina.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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