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Invitrogen
CLYBL Polyclonal Antibody
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Product Details
PA5-59009
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CLYBL. Recombinant protein control fragment (Product #RP-97957).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2639919
Product Specific Information
Immunogen sequence: IVVIAKAFGL QAIDLVYIDF RDGAGLLRQS REGAAMGFTG KQVIHPNQIA VVQEQFSPSP EKIKWAEELI AAFKEHQQLG KGAFTFQGSM IDMPLLKQAQ NTVTLATS
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 93%.
Target Information
CLYBL, also named as CLB, is a Mitochondrial citramalyl-CoA lyase indirectly involved in the vitamin B12 metabolism. It is a human mitochondrial enzyme of unknown function that is found in multiple eukaryotic taxa and conserved to bacteria. It acts as a beta-methylmalate synthase in vitro, by mediating conversion of glyoxylate and propionyl-CoA to beta-methylmalate. There are two isoforms with MW 31-33 kDa and 35-37 kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: (3S)-malyl-CoA thioesterase; bA134O15.1; Beta-methylmalate synthase; Citramalyl-CoA lyase, mitochondrial; Citrate lyase beta-like; Citrate lyase subunit beta-like protein; Malate synthase
Gene Aliases: CLB; CLYBL
UniProt ID: (Human) Q8N0X4
Entrez Gene ID: (Human) 171425
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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