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Invitrogen
CILP Polyclonal Antibody
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FIGURE: 1 / 1
CILP Antibody (PA5-51856) in IHC
International journal of molecular medicine 2021 -
Figure 3 Expression of CILP in human intervertebral disc tissue increases with the degree of degeneration. (A and B) CILP immunohistochemical staining of Pfirrmann grade I (low degree of degeneration of intervertebral disc tissue). (C and D) CILP immunohistochemical staining of Pfirrmann grade III (high degree of degeneration of intervertebral disc tissue). Blue arrow, CILP expression positive; 10x10, zoom ... View More
Product Details
PA5-51856
Applications
Tested Dilution
Publications
Product Specifications
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CILP
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2639822
Product Specific Information
Immunogen sequence: YKHESKLVLR KLQQHQAGEY FCKAQSDAGA VKSKVAQLIV TASDETPCNP VPESYLIRLP HDCFQNATNS FYYDVGRCPV KTCAGQQDNG IRCRDAVQNC CGISKTEERE IQCSGYTLPT K
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 89%.
Target Information
Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein activity. The full-length and the N-terminal domain of this protein was shown to function as an IGF-1 antagonist. An allelic variant of this gene has been associated with lumbar disc disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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