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Invitrogen
CHD2 Polyclonal Antibody
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FIGURE: 1 / 1
CHD2 Antibody (PA5-96471) in WB
Western blot analysis of CHD2 in extracts of various cell lines. Samples were incubated with CHD2 Polyclonal antibody (Product # PA5-96471) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Product Details
PA5-96471
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-223 of human CHD2 (NP_0010360371)
Conjugate
Form
Liquid
Concentration
0.34 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2808273
Product Specific Information
Immunogen sequence: MMRNKDKSQE EDSSLHSNAS SHSASEEASG SDSGSQSESE QGSDPGSGHG SESNSSSESS ESQSESESES AGSKSQPVLP EAKEKPASKK ERIADVKKMW EEYPDVYGVR RSNRSRQEPS RFNIKEEASS GSESGSPKRR GQRQLKKQEK WKQEPSEDEQ EQGTSAESEP EQKKVKARRP VPRRTVPKPR VKKQPKTQRG KRKKQDSSDE DDDDDEAPKR QTR; Positive Samples: Jurkat, DU145, SW620, Mouse lung, Rat brain; Cellular Location: Nucleus
Target Information
The CHD family of proteins is characterized by the presence of chromo domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP-dependent helicase CHD2; CHD-2; Chromodomain-helicase-DNA-binding protein 2; DKFZp547I1315; DKFZp686E01200; DKFZp781D1727; FLJ38614
Gene Aliases: 2810013C04Rik; 2810040A01Rik; 5630401D06Rik; AI851092; BC029703; CHD-2; CHD2; EEOC
UniProt ID: (Human) O14647, (Mouse) E9PZM4
Entrez Gene ID: (Human) 1106, (Rat) 308738, (Mouse) 244059
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
cellular response to DNA damage stimulus
muscle organ development
covalent chromatin modification
DNA duplex unwinding
hematopoietic stem cell differentiation
metabolic process
regulation of transcription, DNA-templated
chromatin modification
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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